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Low-dose naltrexone (LDN) describes the off-label use of the medication naltrexone at low doses for diseases such as Crohn's disease and multiple sclerosis. Naltrexone is typically prescribed for opioid dependence or alcohol dependence, as it is a strong opioid antagonist.
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Kim SW, Grant JE, Yoon G, Williams KA, Remmel RP (2006) Safety of high-dose naltrexone treatment: hepatic transaminase profiles among outpatients.
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